Down Syndrome Day: Pay attention to Down Syndrome and care for "Tang Babies"

Down Syndrome Day: Pay attention to Down Syndrome and care for "Tang Babies"

Down syndrome, also known as trisomy 21 syndrome. In 1866, British doctor Don John Langton first published this disease; In 1959, French geneticist Jerome Le Jong discovered that the disease was caused by a trisomy variation in the 21st pair of chromosomes in the human body; This is also the first disease caused by chromosomal defects discovered by humans

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Fudan University Ge Junbo et al. Revealed CD47-SIRP α Immune checkpoint inhibition of the latest protein degradation strategy

Fudan University Ge Junbo et al. Revealed CD47-SIRP α Immune checkpoint inhibition of the latest protein degradation strategy

As an innate immune checkpoint, CD47-SIRP α The axis plays a crucial role in maintaining tissue homeostasis and the pathophysiological processes of various diseases, including tumor evasion, cardiovascular disease, and stem cell transplantation.

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